Nandini (Aishwarya Rai) is the daughter of Pandit Darbar, renowned proponent of Indian classical music, living in the Rann of Kutch. Nandini has been brought up with more freedom and education than her siblings, as she is the most beloved of Pandit Darbar. Into the family comes Sameer (Salman Khan), a boy of Indo-Italian parentage. He is a music student and wants to grasp the essence of Hindustani music under the guidance of Pandit Darbar. He is a playful person and during the course of his stay Nandini and Sameer fall in love with each other. When their love is discovered, Sameer is banished from the household. Sameer writes to Nandini, but his letters don't reach her in time. Meanwhile, Nandini's parents have arranged to get her married. Nandini goes through the marriage with Vanraj (Ajay Devgan). He is deeply in love with her and all he asks is that they maintain the charade of a happy couple for the sake of his family. They live in this deceit briefly, until Sameer's letters reach Nandini and Vanraj discovers them. He then shows his true love and wisdom by taking Nandini to Italy to search for Sameer. Nandini and Vanraj search for Sameer but always come up against a dead end. During their search, they come across an obstacle, where they are being robbed and Nandini shot by one of the thiefs. She gets hospitalized, and Vanraj selflessly devotes himself to caring for Nandini during her stay in hospital. She sees her husband's adoration for her and wishes to drop the search and go back home. But.. they get news that Sameer will definitely be in a particular place at a particular time. What happens when Nandini sees Sameer? Who does she choose? To find out watch Hum Dil De Chuke Sanam